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Hudson product information:



Hudson Cata#: HB0137

Product Name: TG-02

CAS#: 108605-62-5;

Chemical Formula: C12H9F3N2O2

Exact Mass: 270.06161

Molecular Weight: 270.20727

Purity: 99%

Storage Info: N/A

Synonym: A77 1726; HMR1726

 

Structure Formula:
Price:

Structure Formula Not Available.

1 g / $335.00
2 g / $530.00

Product Info::

N/A

If you want to make an order, please contact 1 (732) 640-2533

or email wzhuang@hudsonbiopharma.com

 

References (Review papers):

1: Pallis M, Abdul-Aziz A, Burrows F, Seedhouse C, Grundy M, Russell N. The multi-kinase inhibitor TG02 overcomes signalling activation by survival factors to deplete MCL1 and XIAP and induce cell death in primary acute myeloid leukaemia cells. Br J Haematol. 2012 Oct;159(2):191-203. doi: 10.1111/bjh.12018. Epub 2012 Aug 30. PubMed PMID: 22934750.

2: Poulsen A, William A, Blanchard S, Nagaraj H, Williams M, Wang H, Lee A, Sun E, Teo EL, Tan E, Goh KC, Dymock B. Structure-based design of nitrogen-linked macrocyclic kinase inhibitors leading to the clinical candidate SB1317/TG02, a potent inhibitor of cyclin dependant kinases (CDKs), Janus kinase 2 (JAK2), and Fms-like tyrosine kinase-3 (FLT3). J Mol Model. 2013 Jan;19(1):119-30. doi: 10.1007/s00894-012-1528-7. Epub 2012 Jul 22. PubMed PMID: 22820730.