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Hudson product information:

Hudson Cata#: HB0124

Product Name: SB743921

CAS#: 941678-49-5

Chemical Formula: C17H18N6

Exact Mass: 306.15929

Molecular Weight: 306.37

Purity: 99%

Storage Info: N/A

Synonym: INCB-018424. trade name: Jakafi


Structure Formula:

Structure Formula Not Available.

10 mg / $210.00
50 mg / $335.00

Product Info::


If you want to make an order, please contact 1 (732) 640-2533

or email wzhuang@hudsonbiopharma.com


References (Review papers):

1: Viswanath AN, Pae AN. Resistance by allostery: a novel perspective for eg5-targeted drug design. J Med Chem. 2013 Aug 22;56(16):6314-6. doi: 10.1021/jm401071u. Epub 2013 Jul 30. PubMed PMID: 23899248.

2: Talapatra SK, Anthony NG, Mackay SP, Kozielski F. Mitotic kinesin Eg5 overcomes inhibition to the phase I/II clinical candidate SB743921 by an allosteric resistance mechanism. J Med Chem. 2013 Aug 22;56(16):6317-29. doi: 10.1021/jm4006274. PubMed PMID: 23875972.