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Hudson product information:



Hudson Cata#: HB0091

Product Name: LY-2157299

CAS#: 193275-84-2

Chemical Formula: C27H31Br2ClN4O2

Exact Mass: 636.05023

Molecular Weight: 638.82

Purity: 98%

Storage Info: N/A

Synonym: Sarasar. Code names: SCH 66336, SCH66336, SCH-66336

 

Structure Formula:
Price:

Structure Formula Not Available.

10mg / $280.00
20 mg / $370.00

Product Info::

N/A

If you want to make an order, please contact 1 (732) 640-2533

or email wzhuang@hudsonbiopharma.com

 

References (Review papers):

1: Dituri F, Mazzocca A, Peidrò FJ, Papappicco P, Fabregat I, De Santis F, Paradiso A, Sabbà C, Giannelli G. Differential Inhibition of the TGF-β Signaling Pathway in HCC Cells Using the Small Molecule Inhibitor LY2157299 and the D10 Monoclonal Antibody against TGF-β Receptor Type II. PLoS One. 2013 Jun 27;8(6):e67109. Print 2013. PubMed PMID: 23826206; PubMed Central PMCID: PMC3694933.

2: Bhola NE, Balko JM, Dugger TC, Kuba MG, Sánchez V, Sanders M, Stanford J, Cook RS, Arteaga CL. TGF-β inhibition enhances chemotherapy action against triple-negative breast cancer. J Clin Invest. 2013 Mar 1;123(3):1348-58. doi: 10.1172/JCI65416. Epub 2013 Feb 8. PubMed PMID: 23391723; PubMed Central PMCID: PMC3582135.