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Hudson product information:



Hudson Cata#: HB0071

Product Name: GDC-0980

CAS#: 888216-25-9

Chemical Formula: C20H20N4O3

Exact Mass: 364.15354

Molecular Weight: 364.3978

Purity: 99%

Storage Info: N/A

Synonym: STA-9090; STA 9090

 

Structure Formula:
Price:

Structure Formula Not Available.

10mg / $180.00
25mg / $340.00

Product Info::

N/A

If you want to make an order, please contact 1 (732) 640-2533

or email wzhuang@hudsonbiopharma.com

 

References (Review papers):

1: English DP, Bellone S, Cocco E, Bortolomai I, Pecorelli S, Lopez S, Silasi DA, Schwartz PE, Rutherford T, Santin AD. Oncogenic PIK3CA gene mutations and HER2/neu gene amplifications determine the sensitivity of uterine serous carcinoma cell lines to GDC-0980, a selective inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2). Am J Obstet Gynecol. 2013 Nov;209(5):465.e1-9. doi: 10.1016/j.ajog.2013.07.020. Epub 2013 Jul 24. PubMed PMID: 23891627.

2: Salphati L, Pang J, Plise EG, Lee LB, Olivero AG, Prior WW, Sampath D, Wong S, Zhang X. Preclinical assessment of the absorption and disposition of the phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor GDC-0980 and prediction of its pharmacokinetics and efficacy in human. Drug Metab Dispos. 2012 Sep;40(9):1785-96. doi: 10.1124/dmd.112.046052. Epub 2012 Jun 13. PubMed PMID: 22696419.