English | 中文

Hudson product information:

Hudson Cata#: HB0014

Product Name: ARRY-520

CAS#: 885060-09-3

Chemical Formula: C20H22F2N4O2S

Exact Mass: 420.14315

Molecular Weight: 477.43

Purity: > 97%

Storage Info: two years -20°C

Synonym: N/A


Structure Formula:

Structure Formula Not Available.

5mg / $185.00
10mg / $300.00

Product Info::


If you want to make an order, please contact 1 (732) 640-2533

or email wzhuang@hudsonbiopharma.com


References (Review papers):

1: Khoury HJ, Garcia-Manero G, Borthakur G, Kadia T, Foudray MC, Arellano M, Langston A, Bethelmie-Bryan B, Rush S, Litwiler K, Karan S, Simmons H, Marcus AI, Ptaszynski M, Kantarjian H. A phase 1 dose-escalation study of ARRY-520, a kinesin spindle protein inhibitor, in patients with advanced myeloid leukemias. Cancer. 2012 Jul 15;118(14):3556-64. doi: 10.1002/cncr.26664. Epub 2011 Dec 2. PubMed PMID: 22139909.

2: Tunquist BJ, Woessner RD, Walker DH. Mcl-1 stability determines mitotic cell fate of human multiple myeloma tumor cells treated with the kinesin spindle protein inhibitor ARRY-520. Mol Cancer Ther. 2010 Jul;9(7):2046-56. doi: 10.1158/1535-7163.MCT-10-0033. Epub 2010 Jun 22. PubMed PMID: 20571074.